Iontophoresis and Phonophoresis as a Transdermal Technique for Drug Delivery
ثبت نشده
چکیده
Description of Procedure or Service Iontophoresis is a method of transdermal local drug delivery using electrical current. A charged, ionic drug is placed on the skin with an electrode of the same charge, allowing direct current to drive the drug into the skin. Ultrasound transdermal delivery involves the use of ultrasonic energy to enhance delivery of solutes either simultaneously or via pre-treatment, and is referred to as sonopheresis or phonophoresis.
منابع مشابه
Synergistic Effect of Chemical Enhancer And Iontophoresis For Transdermal Delivery Of Nebivolol Hydrochloride
The aim of the present study was to develop and investigate the feasibility of delivering Nebivolol as a transdermal patch by iontophoresis. The passive and electrically assisted transdermal delivery of Nebivolol hydrochloride by iontophoresis will improve the therapeutic efficacy and overcome the difficulties raised in oral drug delivery. Because of its extensive hepatic metabolism and low dos...
متن کاملEnhanced Transdermal Delivery of Granisetron by Using Iontophoresis
The purpose of the present study was to explore the passive and electrically assisted transdermal transport of Granisetron hydrochloride (GRA) in solution and gel formulation through iontophoresis and also the feasibility of delivering therapeutic amounts of drug for the treatment of chemotherapy-induced nausea and vomiting. In this study, iontophoretic permeation of GRA through guinea pig...
متن کاملEnhanced Transdermal Delivery of Granisetron by Using Iontophoresis
The purpose of the present study was to explore the passive and electrically assisted transdermal transport of Granisetron hydrochloride (GRA) in solution and gel formulation through iontophoresis and also the feasibility of delivering therapeutic amounts of drug for the treatment of chemotherapy-induced nausea and vomiting. In this study, iontophoretic permeation of GRA through guinea pig...
متن کاملA Review on Current Status and Future Potential of Transdermal Patches as a Promising Drug Delivery System
Transdermal patches are now widely used in topical and transdermal drug delivery systems (TDDS). Up to now, TDDS has been used in several conditions, such as smoking cessation, analgesic effect, nausea, contraception, and hormone therapy. Basically, there are two types of transdermal patches: the reservoir-type patches and the matrix-type patches. First generation TDDS were designed for deliver...
متن کاملLiquid Transdermal Drug Delivery: The State of the TDS® Art
To date, transdermal delivery has been effective in delivering only a very few drugs due to diffi culties in moving larger, and chemically non-compatible, molecules across the skin’s biologically-active barrier. Drugs with higher melting points, drugs of molecular weight greater than 500 Daltons and drugs requiring pharmacological doses of more than 40 mg in 24 hours can not employ patchor gel-...
متن کامل